| | A blast of super-cold arctic air is bringing dangerous sub-zero cold to the U.S. Midwest and Northeast as the system cartwheels through the Dakotas into Chicago, Illinois, and on to New England. | | | President Donald Trump expressed skepticism on Sunday that U.S. lawmakers seeking to avoid another government shutdown could reach a deal on border security that he would accept, as he renewed his vow to build a wall on the southern border with Mexico. | | | The one-time billionaire founder of Insys Therapeutics Inc and four other former executives and managers of the opioid drugmaker will face trial over charges they conspired to pay doctors bribes to prescribe patients an addictive fentanyl spray to boost sales. | | | With federal prosecutors expected to rest their case against Joaquin "El Chapo" Guzman on Monday, lawyers for the accused Mexican drug kingpin have given few clues about how they plan to counter three months of testimony by more than 50 government witnesses. | | | A deep freeze is forecast to hit the U.S. Midwest this week, with snow, brutally cold temperatures and potentially life-threatening wind chill across northern Illinois and northwest Indiana by midweek, the National Weather Service said. | | | When Danny Reagan was 13, he began exhibiting signs of what doctors usually associate with drug addiction. He became agitated, secretive and withdrew from friends. He had quit baseball and Boy Scouts, and he stopped doing homework and showering. | | | Sheriff's deputies in Virginia on Sunday arrested a 21-year-old man wanted on suspicion of shooting five people to death in Louisiana including his parents, his girlfriend and members of her family. | | | An official at the Duke University School of Medicine stepped down, a day after she was denounced by students on social media for sending an email saying Chinese students should speak English on campus. | | | Minutes after President Donald Trump announced an end to the longest U.S. government shutdown in history on Friday, Yvette Hicks' phone started ringing. | | | President Donald Trump, who famously vowed to negotiate big deals in the White House, came out of a government shutdown battle on Friday politically wounded and outmaneuvered by U.S. House of Representatives Speaker Nancy Pelosi. | | | | |