| | The U.S. Centers for Disease Control and Prevention (CDC) said on Wednesday it plans to make the rapidly spreading monkeypox disease a nationally notifiable condition. | | | The U.S. Justice Department has opened a criminal investigation into Cassava Sciences Inc involving whether the biotech company manipulated research results for its experimental Alzheimer's drug, two people familiar with the inquiry said. | | | GSK Plc said on Wednesday the U.S. Food and Drug Administration had cleared its kidney disease drug Benlysta for the treatment of children aged 5 to 17 years. | | | People lined up on Wednesday for the monkeypox vaccine at a new dedicated vaccine centre in Paris, which has been booked out for two days since opening. | | | Bristol Myers Squibb Co said on Wednesday it had transferred its commercial operations in Russia to a third-party distributor and incurred $39 million in related costs. | | | U.S. President Joe Biden said on Wednesday he will now be able to return to work in person after testing negative for COVID-19, adding that he was "feeling great." | | | Indian state research body ICMR said it has isolated the monkeypox virus and is inviting vaccine makers to consider making shots after the country reported some cases of infection. | | | The Pan American Health Organization (PAHO) said on Wednesday that nearly 5,300 monkeypox cases have so far been reported across 18 countries and territories in the Americas, with the majority in the United States, Canada and Brazil. | | | Drugmaker Bavarian Nordic said U.S. and European regulators have approved the use of Jynneos vaccine doses made at the company's plant in Denmark as global efforts to tackle the monkeypox outbreak pick up pace. | | | Drugmaker Merck & Co avoided billions of dollars of U.S. taxes in recent years on its top-selling cancer drug Keytruda by booking all the profits from the treatment outside of the United States, according to an ongoing investigation by Democrats on the Senate Finance Committee. | | | | |